421 Meridian Avenue 21
Rare South of Fifth Penthouse Loft | Exceptional Investment & Second-Home OpportunityDiscover sophisticated Miami Beach living in this expansive three-story penthouse loft, the largest and most private residence at Meridian 5, ideally located in the coveted South of Fifth neighborhood. Just three blocks from the beach and moments from some of Miami Beach’s finest dining, shopping, and entertainment, this exceptional residence offers the perfect blend of privacy, space, and location.Fully furnished and filled with natural light, the residence features dramatic 20-foot ceilings, motorized shades, and a modern kitchen with stainless steel appliances. The thoughtfully designed three-level layout includes a private lower-level bedroom and full bath, a spacious Primary Suite with its own private terrace, and an exclusive rooftop deck offering breathtaking views of the Miami skyline.Residents enjoy access to a sun-drenched pool, along with deeded covered parking—an exceptional convenience in South of Fifth. With the flexibility to serve as a luxurious primary residence, second home, or investment property, the unit offers rental potential of up to 12 times per year, providing an attractive opportunity in one of Miami Beach’s most sought-after neighborhoods.A rare combination of size, privacy, outdoor space, and location, this distinctive penthouse loft presents an exceptional opportunity to own in South of Fifth.
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Listed by Douglas Elliman · 305-695-6060
Listing data comes from the participating MLS and is provided for consumers’ personal, non-commercial use. It may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Properties shown may be listed by brokerages other than Pure Equity Realty LLC, and are marked with the listing office’s name. Information is deemed reliable but is not guaranteed accurate by the MLS or by Pure Equity Realty LLC, and should be independently verified. Data last updated October 16, 2026.